US plans to close Chemical Safety Board by October
Government says CSB duplicates capabilities in other agencies
Sanofi to buy Blueprint Medicines for over $9 billion
Blueprint has one approved drug and enhances Sanofi’s immunology portfolio
Safety is everyone’s responsibility
Maintaining culture and investment is key, especially in the absence of incidents
Crispr Nobel laureates get another chance to claim ownership in long-running patent dispute
Jennifer Doudna and Emmanualle Charpentier could recoup patent rights to the gene-editing technology, thanks to ruling from US appeal court
Polymer membrane separates hydrocarbons, offering alternative to distillation
Explosion and fire at Chinese chemical plant kills five
Ignoring women’s health shouldn’t be an option
Women are not just another confounding factor in drug development
Trade deals stave off Trump’s tariffs temporarily
US approves natural food dyes while pushing to phase out synthetic colours
Highlights
Making genetically engineered food palatable
The next generation of genetically altered food is forging ahead, aiming to be attractive to consumers rather than producers. Katrina Megget finds out whether Crispr means crisper salads
The glyphosate debate
The EU has recently approved the use of glyphosate for another decade. Bárbara Pinho examines the controversial pesticide’s presence in British farming and considers the possibility of a ban in the UK
Putting the F in pharma
Adding fluorine to drug molecules can be tricky, but is often worthwhile. Rachel Brazil talks to the chemists trying to tame the ninth element
On the trail of the male contraceptive pill
As multiple novel male contraception compounds enter clinical trials, is family planning about to undergo a second revolution? James Mitchell Crow reports
The promise of drugs that send proteins to the shredder
Andy Extance charts how research into revolutionary targeted protein degradation therapies is moving from serendipity to strategic discovery
Sanofi to buy Blueprint Medicines for over $9 billion
Blueprint has one approved drug and enhances Sanofi’s immunology portfolio
Modelling amorphous solid dispersion (ASD) release mechanisms
Join us on 10 June to learn how thermodynamic modelling and molecular simulation can help our understanding of amorphous solid dispersion
Women are not just another confounding factor in drug development
Ignoring physiological differences between the sexes is indefensible
Improving women’s health research will benefit everyone
Fixing the inequality is morally just, and economically sound
US plans to close Chemical Safety Board by October
Government says CSB duplicates capabilities in other agencies
Explainer: Why is the UK banning disposable vapes?
Prior to the ban, almost seventy million single-use e-cigarettes were being discarded each year in the UK – containing enough lithium for a thousand electric vehicle batteries
Ignoring women’s health shouldn’t be an option
Developing therapies for conditions that predominantly affect women is a neglected, but enormous, opportunity
US approves natural food dyes while pushing to phase out synthetic colours
Government sets voluntary goal of removing artificial colours by 2027
Iran port explosion highlights issues of shipping hazardous chemicals
Intersecting regulations and jurisdictions mean rules can be accidentally or deliberately overlooked
Giving companies room to grow
Can shopping centres and offices become urban lab spaces for innovative companies to grow and scale-up?
Polymer membrane separates hydrocarbons, offering alternative to distillation
Microporous membrane enables energy efficient chemical separations
Improving propylene synthesis using light-activated catalysis could cut emissions
Single-atom photocatalyst makes propylene at milder temperatures
Generative AI pipeline creates promising antimicrobial peptides
AI model extrapolates beyond training data to predict diverse antimicrobial structures
Far more drugs could be taken orally by formulating them with silica nanoparticles
Many more medicines could be made water soluble making taking them easier for patients
Mapping metabolite disturbances by drugs
High-throughput metabolomic profiling gives insight into unpredictable drug effects
Metal–organic framework captures carbon dioxide at industrially relevant temperatures
Material could improve energy efficiency of capturing carbon from industy’s exhaust gases
Fluorspar to fluorine chemicals without going via hazardous hydrogen fluoride
Safer way to turn calcium fluoride mineral into valuable industrial materials
Banned pigments found in tattoo inks sold in the EU
Nine out of 10 green and blue inks analysed violate Reach regulations
Explosion and fire at Chinese chemical plant kills five
Six others missing and 19 injured at Shandong Youdao Chemical
Government reduces UK Reach fees by ‘£40 million’
Registration fees for most chemicals reduced, but uncertainty remains over safety data requirements
Polymer membrane separates hydrocarbons, offering alternative to distillation
Microporous membrane enables energy efficient chemical separations
Trade deals stave off Trump’s tariffs temporarily
Initial agreements with China and UK have paused trade war, but uncertainty reigns
Explosion and fire at Chinese chemical plant kills five
Six others missing and 19 injured at Shandong Youdao Chemical
US approves natural food dyes while pushing to phase out synthetic colours
Government sets voluntary goal of removing artificial colours by 2027
The hole in the UK chemical industry
Norman Keane thinks ICI’s breakup has left a gap in scale-up knowhow and skills, as well as a lack of facilites
The problem of scale-up in the UK
What’s the point of knowledge generation if we’re not creating high value jobs, asks Chris Kay
BioLab fined for fire and chemical plume at US plant
‘Improperly stored’ pool chemicals reacted with water to release chlorine
Government reduces UK Reach fees by ‘£40 million’
Registration fees for most chemicals reduced, but uncertainty remains over safety data requirements
Sanofi to buy Blueprint Medicines for over $9 billion
Blueprint has one approved drug and enhances Sanofi’s immunology portfolio
Merck KGaA to buy cancer specialist SpringWorks
$3.9 billion deal boosts Merck’s pipeline as it faces patent expiries
Dow to cut 1500 jobs as global chemicals industry reshapes
US firm joins other industry heavyweights in shedding jobs to cut costs
J&J’s Intra-Cellular deal could signal more mega-mergers for 2025
£15 billion deal for neuroscience biotech aims to replace revenues from patent expiries
Optimise drug discovery: predicting transporter-mediated drug interactions
Learn how in vitro models, biomarkers and modelling can improve prediction of drug interactions and toxicity – reducing false positives and unnecessary clinical studies
Pass or fail: rapid polymer analysis with FTIR
Your guide to quick and reliable verification of polymers with the Lyza 7000 FTIR spectrometer
Illuminating progress: recent advances in photoredox catalysis
In this free download, shed some light on the latest developments in photoredox for drug development and materials science
